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Great Mills is located in Saint Mary's County, Maryland. There are roughly 5,097 residents, living in 1,834 households. The average temperature for Great Mills this time of the year is low of 54F and high of 75F. On average, Great Mills gets about 4.2 inches of precipitation in May. Most residents are home owners (70%), have a post secondary degree (51%) and are single, no kids (33%).