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Manistee is located in Manistee County, Michigan. There are roughly 5,128 residents, living in 2,326 households. The average temperature for Manistee this time of the year is low of 53F and high of 75F. On average, Manistee gets about 3.25 inches of precipitation in June. Most residents are home owners (58%), have a post secondary degree (53%) and are single, no kids (49%).