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De Witt is located in Onondaga County, New York. There are roughly 25,847 residents, living in 10,306 households. The average temperature for De Witt this time of the year is low of 46F and high of 68F. On average, De Witt gets about 3.48 inches of precipitation in May. Most residents are home owners (72%), have a post secondary degree (51%) and are single, no kids (42%).