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Port Saint Lucie is located in Saint Lucie County, Florida. There are roughly 168,005 residents, living in 62,475 households. The average temperature for Port Saint Lucie this time of the year is low of 67F and high of 86F. On average, Port Saint Lucie gets about 4.62 inches of precipitation in May. Most residents are home owners (77%), have a high school diploma (49%) and are married, no kids (33%).