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Sanibel Island is located in Lee County, Florida. There are roughly 7,405 residents, living in 3,829 households. The average temperature for Sanibel Island this time of the year is low of 67F and high of 87F. On average, Sanibel Island gets about 3.53 inches of precipitation in May. Most residents are home owners (85%), have a post secondary degree (66%) and are married, no kids (55%).