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Simpsonville is located in Greenville County, South Carolina. There are roughly 15,000 residents, living in 5,801 households. The average temperature for Simpsonville this time of the year is low of 47F and high of 73F. On average, Simpsonville gets about 3.61 inches of precipitation in April. Most residents are home owners (68%), have a post secondary degree (54%) and are single, no kids (35%).